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Presentations: Management Session

Whirlpool
Simulation Supporting a Lean Implementation
Project Management for Drug Discovery - Pfizer Global R&D
Simulation and the Learning Organization
A Call to Arms - Take the Lead in System Innovation
Scheduling Visualization to Evaluate Resource Change Initiative in a Bio-Pharma Environment
Assessing the Impact of Clinical Study Speed Targets on Portfolio Yield
Simulation Modeling & Design for Six Sigma (DFSS)

 

 


Presentations

Del Halling, Whirlpool

Highlights:•Supply chain•Inventory management•TransportationWhirlpool produces and sells appliances of many sizes and functionalities. Their manufacturing plants produce specific families of products for distribution to an almost infinite number of end-customer sites (distribution centers, major appliance retail outlets, individual consumer homes, etc.) throughout North America. To service this distribution, Whirlpool has used a well established system of factories, regional distribution centers, and local distribution centers. Adjustments to the network were simulated to identify if the desired improvements will be achieved.This project analyzes the inventory management at the distribution centers and the transportation constraint of the supply chain and verifies the new network design. The analysis includes min/max of inventory levels, lead time of replenishment, common carrier loading and movement time, service level calculations, and inventory rise/fall over time.


SIMULATION SUPPORTING A LEAN IMPLEMENTATION – TWO EXAMPLES
Claus Weidinger - REOSS International

Any lean implementation – or implementation in general – has one big weakness: it is based on static data. In the case of lean, the customer demand as a basis is highly variable and can change on a daily basis. The presented subject shows how to overcome this issue by using the tools of simulation. The first example demonstrates a simulation of the logistics for an automotive manufacturer with a serial production character. The second example shows the simulation of a flow line implementation of a highly customized motor manufacturer. Both cases show the potential pitfalls that were avoided by the simulation.

 



PROJECT MANAGEMENT FOR DRUG DISCOVERY
Mike Vanderspool & Melinda Durgin, Pfizer Global R&D

The Pharmaceutical industry continues to be under escalating pressure to discover and develop new drugs faster in an environment of increasing regulatory hurdles, environmental scrutiny, and tough price competition. These demands translate into a need for greater productivity and efficiency from the Research and Development process. To help meet this challenge, the PDM Department of Pfizer Global R & D is utilizing ProModel’s Portfolio Simulator to efficiently and effectively project resources required to support the Discovery efforts of new medicines.

 



SIMULATION AND THE LEARNING ORGANIZATION
Rob Bateman, ProModel

Advances in simulation over the last four decades have consistently made the technology easier to use. Techniques that were once limited to specialist programmers in dedicated facilities are now available to engineers and business analysts on laptop computers. The time spent building models is in many cases significantly less than the time spent gathering data. We are applying simulation to many problems that would have been avoided in the past, based on time requirements and engineering cost. The number of models created by a relatively small number of simulation experts has increased dramatically. Why then has the use of simulation not grown as fast as the demand for other technologies?Part of the answer is that we are still guilty of keeping the knowledge to ourselves. Since Peter Senge published The Fifth Discipline in 1990, management experts have told us that every business should become a learning organization. Although simulation allows us to answer important questions, and we do, our use of models to help others within the company understand production or service issues has often been weak. Uniquely among operations research tools, we have the ability to actually help others see concepts in action. This advantage alone should make simulation the technique of choice for projects in which a successful outcome depends on the understanding and input of people who come from different perspectives. We should be taking the lead in spreading information and creating understanding throughout the organization.In 1971, a German philosopher suggested that operations research techniques should be used to emancipate or empower people. Other forms of simulation and visualization are now being used to encourage public input in government decision making and promote citizen participation. Does discrete-event simulation allow us to transfer knowledge and encourage the discussion of multiple perspectives in our own organizations? The presentation will discuss, as an example, a project in China where simulation helped everyone involved in a new process have a voice.

 


A Call to Arms - Take the Lead in System Innovation
Peter Kalish, GE Global Research
Operations Leader, Pilot Development Cente
r

Through the last two decades of the 20th century, corporate success was defined by operational excellence. Those companies that could out-negotiate, out-hire, out-invest and out-perform in a given market were the winners. GE, under the leadership of Jack Welch, was the archetype of the corporate competitor. GE set new corporate standards for leadership training, talent development and retention, quality control, acquisition integration and financial engineering. But times have changed. Fueled by the increasing transparency of the world - through accessibility afforded by mobile communications, shared experience via the web and global awareness provided by satellite broadcasts - markets are now more demanding.

This presentation will explore the impact afforded by dynamic models - simulations - prior to new product launch, through mainstream demand escalation and into the beginnings of commoditization. I will discuss techniques that can be used to influence decisions, identify risks and enhance the corporation's shared vision of the future. While examples of successful simulations will be cited, this will not be a deep dive into those applications. Rather, I will issue a call to arms for those with the initiative to put their modeling expertise to work in today's accelerated business climate.

 


SCHEDULING VISUALIZATION TO EVALUATE RESOURCE CHANGE INITIATIVES IN A BIO-PHARMA ENVIRONMENT
Kurt Shampine & Jim Rodgers, ProModel


One of the more difficult situations that any Bio-Pharma production process has to deal with is the effects of product expiry on their capacity and how dramatically that changes with every production improvement initiative that is attempted. This solution and presentation illustrates how simulation teamed with an output Gantt Chart schedule visualization can be utilized to hurdle the uncertainties that arise when making major changes. This solution also allows the user to deal with eliminating expiry times as well as scheduling the highly sensitive media and buffer prep steps while testing major production initiatives like adding a third shift to the environment.

 


ASSESSING THE IMPACT OF CLINICAL STUDY SPEED TARGETS ON PORTFOLIO YIELD
Alan Poirier, Pfizer


Every Pharmaceutical company must deliver clinical trials to standards of quality, speed and cost. This analysis looks at the performance of individual segments of clinical studies, and asks - if you have an understanding of the range of potential improvement that is possible, where would you focus your process improvement initiatives? The analysis uses industry benchmarks to assess what's possible, develop several performance scenarios which are applied to the entire Pharmaceutical portfolio, looking at the scenario impact on several Key Performance Indicators (KPIs).

 


SIMULATION MODELING & DESIGN FOR SIX SIGMA (DFSS)
Greg Gordon, Merck & Co


Merck is in the process of becoming a Six Sigma Company. The strategy is to make Design For Six Sigma (DFSS) and Lean part of the Merck culture. In the past Merck has used simulation modeling as a capacity planning tool. By incorporating ProModel into DFSS and LEAN simulation modeling is being used from concept through to daily production planning and scheduling. Where and to what extent discrete simulation should be used in DFSS and Lean is a major topic within Merck at this time. (Presentation download unavailable.)


 

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